Accepted for Publication: August 29, 2013.
Published Online: December 9, 2013. doi:10.1001/jamaneurol.2013.5007.
Study concept and design: Lev, Koroshetz, Nogueira.
Acquisition of data: Lima, Furie, Silva, Lev, Camargo, Singhal, Harris, Koroshetz, Smith.
Analysis and interpretation of data: Lima, Furie, Lev, Halpern, Nogueira.
Drafting of the manuscript: Lima, Nogueira.
Critical revision of the manuscript for important intellectual content: Furie, Silva, Lev, Camargo, Singhal, Harris, Halpern, Koroshetz, Smith.
Statistical analysis: Lima, Halpern, Nogueira.
Obtained funding: Lev.
Administrative, technical, or material support: Furie, Lev.
Study supervision: Lev, Koroshetz.
Conflict of Interest Disclosures: Dr Lev is a speaker for and receives educational support from GE Healthcare. Dr Singhal receives research support from the NIH/National Institute of Neurological Disorders and Stroke, Pfizer, and PhotoThera; serves on event adjudication committees for the Thrombolysis in Myocardial Infarction Study Group; and has served as a medical expert witness in individual cases concerning stroke in young adults. Dr Smith has served on scientific advisory boards for Stryker/Concentric Medical. Dr Nogueira has served on scientific advisory boards for Stryker/Concentric Medical, Covidien/ev3 Neurovascular, CoAxia, Penumbra, Rapid Medical, Reverse Medical, and Neurointervention. No other disclosures were reported.
Funding/Support: This research was funded by grant RO1-HS011392-01A1 from the US Department of Health and Human Services/Agency for Healthcare Research and Quality.
Role of the Sponsor: The funding agencies had no role in the design and conduct of the study; collection, management, analysis, or interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.