Accepted for Publication: February 19, 2013.
Published Online: August 19, 2013. doi:10.1001/jamaneurol.2013.443.
Acquisition of data: Tazen, Figueroa, Goldman, Pulst, Kuo.
Analysis and interpretation of data: Tazen, Kwan, Sampson, Gutmann, Pulst, Mitsumoto, Kuo.
Drafting of the manuscript: Tazen, Kuo.
Critical revision of the manuscript for important intellectual content: All authors.
Obtained funding: Pulst.
Administrative, technical, or material support: Figueroa.
Study supervision: Tazen, Hunt, Gutmann, Pulst, Mitsumoto, Kuo.
Conflict of Interest Disclosures: Pulst has received consulting fees from Athena Neurosciences; has received funding from grants RC4NS073009 and R01 NS033123 from the National Institutes of Health; has a pending stem-cell patent; and periodically receives royalties from Cedars-Sinai Health Systems. Mitsumoto has received grants from Teva, Avanir, Knopp Biosciences, Biogen Idec, and Cytokinetics for clinical trials; has received honoraria for participating in advisory board meetings from Avanir, Sanofi-Aventis, Chionogi, and Biogen Idec; is now a member of the Data Safety Monitoring Board for the NeuralStem clinical trial; has received honoraria from Sanofi-Aventis Japan for giving seminars at the annual meetings of the Japanese Neurological Society in 2009 and 2010 in Japan; and has received a conference grant to Columbia University for the 2011 International ALS Conference from the National Institute of Neurological Disorders and Stroke, Office of Rare Diseases Research, Muscular Dystrophy Association, ALS Association, ALS Society of Canada, Adams Foundation, Ride for Life, ALS Hope Foundation, Les Turner Foundation, Sanofi-Aventis, Biogen Idec, Knopp Biosciences, and Avanir. No other disclosures were reported.
Funding/Support: This work was supported by a research fellowship from the American Academy of Neurology, grant R01 NS033123 from the National Institutes of Health, and the Parkinson’s Disease Foundation.