Accepted for Publication: April 23, 2013.
Published Online: August 19, 2013. doi:10.1001/jamaneurol.2013.3268.
Acquisition of data: Noreau, Bourassa, Szuto, Levert, Dobrzeniecka, Gauthier, Forlani, Durr, Anheim, Stevanin, Brice, Dupré.
Analysis and interpretation of data: Noreau, Anheim, Bouchard.
Drafting of the manuscript: Noreau, Durr, Brice, Dion.
Critical revision of the manuscript for important intellectual content: Bourassa, Szuto, Levert, Dobrzeniecka, Gauthier, Forlani, Anheim, Stevanin, Bouchard, Dion, Dupré, Rouleau.
Statistical analysis: Noreau.
Administrative, technical, and material support: Noreau, Bourassa, Szuto, Levert, Dobrzeniecka, Gauthier, Forlani, Anheim, Stevanin.
Study supervision: Gauthier, Anheim, Dion, Dupré, Rouleau.
Conflict of Interest Disclosures: None reported.
Funding/Support: Ms Noreau has received the Frederick Banting and Charles Best Graduate Scholarship doctoral award from the Canadian Institutes of Health Research (CIHR).
Additional Information: Dr Rouleau holds the Canada Research Chair and a Jeanne-et-J.-Louis-Levesque Chair for the Genetics of Brain Diseases.
Additional Contributions: We thank the patients involved in this study. Anne Desjarlais, MSc, and Pierre Provencher, BSc, provided patient collection and organization.