Accepted for Publication: September 25, 2012.
Published Online: May 27, 2013. doi:10.1001/jamaneurol.2013.1062.
Study concept and design: Doré, Acosta, Ellis, Masters, Ames, Salvado, and Rowe.
Acquisition of data: Ellis and Ames.
Analysis and interpretation of data: Doré, Villemagne, Bourgeat, Fripp, Chetélat, Zhou, Martins, Ames, and Salvado.
Drafting of the manuscript: Doré, Zhou, and Ames.
Critical revision of the manuscript for important intellectual content: Villemagne, Bourgeat, Fripp, Acosta, Chetélat, Martins, Ellis, Masters, Ames, Salvado, and Rowe.
Statistical analysis: Doré.
Obtained funding: Ellis, Masters, Ames, Salvado, and Rowe.
Administrative, technical, and material support: Bourgeat, Fripp, Ellis, Ames, Salvado, and Rowe.
Study supervision: Villemagne, Fripp, Ellis, Ames, and Salvado.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was supported by the Science and Industry Endowment Fund.