Images in Neurology |

Nocturnal Cramps:  A Nerve Problem

Marco Luigetti, MD; Fioravante Capone, MD; Massimo Del Bene, MD; Federico Ranieri, MD; Vincenzo Di Lazzaro, MD
JAMA Neurol. 2013;70(6):792. doi:10.1001/jamaneurol.2013.1943.
Text Size: A A A
Published online


A 43-year-old woman was admitted to our department to investigate a 6-month history of nocturnal cramps and pain in her left leg. She denied significant prior illness or medication use. The pain was intermittent, was exacerbated by a lying position, and radiated from the proximal posterior part of the left lower limb to the medial malleolus. Findings on neurological examination, including deep palpation of the posterior part of the left thigh, were unremarkable. Tinel sign was absent.

Figures in this Article

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview


Place holder to copy figure label and caption
Graphic Jump Location

Figure. Magnetic resonance imaging neurography of the left leg (A-C), clinical photograph from surgery (D), and histological analysis (E and F). Coronal T1-weighted magnetic resonance imaging neurography revealed an isointense (compared with skeletal muscle), 2.6 × 2.0-cm mass (arrow) (A) with uniform postgadolinium enhancement (arrow) (B). Axial fat-saturated T2-weighted magnetic resonance imaging showed the tumor to be hyperintense (arrow) (C). Surgery confirmed the presence of a capsulated tumor (D). Histological analysis of the benign Schwannoma showed nerve bundles (E, hematoxylin-eosin) positive for S-100 protein immunostaining (F) (original magnification ×20).




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Topics