Accepted for Publication: August 7, 2012.
Published Online: December 17, 2012. doi:10.1001/2013.jamaneurol.211
Author Contributions:Study concept and design: Erbayat Altay, Fisher, Jones, Hara-Cleaver, Lee, and Rudick. Acquisition of data: Erbayat Altay, Fisher, Hara-Cleaver, and Rudick. Analysis and interpretation of data: Erbayat Altay, Fisher, Jones, Lee, and Rudick. Drafting of the manuscript: Erbayat Altay, Lee, and Rudick. Critical revision of the manuscript for important intellectual content: Erbayat Altay, Fisher, Jones, Hara-Cleaver, Lee, and Rudick. Statistical analysis: Lee and Rudick. Obtained funding: Rudick. Administrative, technical, and material support: Fisher, Jones, and Hara-Cleaver. Study supervision: Fisher.
Conflict of Interest Disclosures: Dr Fisher received consulting fees and research funds from Biogen Idec and Genzyme. Dr Rudick received consulting fees or honoraria from Biogen Idec, Novartis, Genzyme-Bayer, Wyeth, and Pfizer and royalties from Informa Healthcare. Ms Hara-Cleaver has received personal compensation as a consultant or speaker from Biogen Idec, Novartis, Teva, Serono, and Acorda.
Funding/Support: This study was supported by National Institutes of Health grants P50NS38667 and UL1 RR024989. Drs Fisher and Rudick and Ms Lee received support (paid to institution) for this project via National Institutes of Health–National Institute of Neurological Disorders and Stroke grant P50 NS 38667 (2004-2009), Project 4 P01NS38667.