Accepted for Publication: April 4, 2012.
Published Online: June 18, 2012. doi:10.1001/archneurol.2012.1117
Author Contributions: Dr Yaffe has full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Yaffe and Rosano. Acquisition of data: Simonsick, Satterfield, Cauley, and Harris. Analysis and interpretation of data: Yaffe, Falvey, Hamilton, Schwartz, Simonsick, Rosano, Launer, and Strotmeyer. Drafting of the manuscript: Yaffe, Falvey, and Hamilton. Critical revision of the manuscript for important intellectual content: Schwartz, Simonsick, Satterfield, Cauley, Rosano, Launer, Strotmeyer, and Harris. Statistical analysis: Hamilton. Obtained funding: Yaffe, Simonsick, Cauley, and Harris. Administrative, technical, and material support: Falvey, Simonsick, Satterfield, Cauley, and Harris.
Financial Disclosure: Dr Yaffe has served on data safety monitoring boards for Pfizer Inc, Medivation Inc, and the National Institutes of Health (NIH) (National Institute of Mental Health and National Institute on Aging [NIA] trials) and has received research support from the NIH (NIA, National Institute of Diabetes and Digestive and Kidney Diseases, and National Institute of Mental Health), the Department of Defense, American Health Assistance Foundation, Anonymous Foundation, and the Alzheimer's Association. Dr Schwartz serves on a scientific advisory board for GlaxoSmithKline; has received speaker honoraria from Amgen and Merck Serono; has received funding for travel from Amgen; and receives research support from Merck Serono, GlaxoSmithKline, and the NIH (National Institute of Diabetes and Digestive and Kidney Diseases and NIA). Dr Simonsick serves as an associate editor for the Journal of Gerontology Medical Sciences. Dr Satterfield receives research support from the NIH/NIA. Dr Cauley receives research support from Novartis. Dr Launer receives research support from the NIH/NIA Intramural Research Program. Dr Harris receives research support from the NIH.
Funding/Support: This work was supported by NIA contracts N01-AG-6-2101, N01-AG-6-2103, and N01-AG-6-2106; NIA grant R01-AG028050; and National Institute of Nursing Research grant R01-NR012459. This research was supported in part by the Intramural Research Program of the NIH, NIA, and grant A201-0029 from the American Health Assistance Foundation. Dr Yaffe is supported in part by NIA grant K24AG031155.
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