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Correspondence |

Acute Hypercalcemia Following Excessive Calcium Supplementation in a Dehydrated Patient With Progressive Multiple Sclerosis: Vitamin D Supplementation Is a Red Herring

Heather E. Hanwell, PhD; Samantha M. Kimball, MLT, PhD
Arch Neurol. 2012;69(6):793-794. doi:10.1001/archneurol.2012.200.
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Marcus et al1 described a patient with progressive multiple sclerosis presenting with symptomatic hypercalcemia. As emphasized by the title of their article, the authors concluded that hypercalcemia was at least partly due to vitamin D toxicity. We disagree. Vitamin D did not play a role in this case of hypercalcemia. Rather, the patient's clinical and biochemical presentation, and especially the successful resolution simply by rehydrating with saline, is entirely consistent with a dehydrated patient who consumed excessive calcium.

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June 1, 2012
Jacqueline F. Marcus, MD; Douglas S. Goodin, MD; Charles A. Harris, MD, PhD; S. Andrew Josephson, MD
Arch Neurol. 2012;69(6):793-794. doi:10.1001/archneurol.2012.203.
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