Accepted for Publication: February 25, 2012.
Published Online: June 11, 2012. doi:10.1001 /archneurol.2012.437
Author Contributions: All authors had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Jacob, Webster, Hilton-Jones, and Vincent. Acquisition of data: Jacob, Viegas, Leite, Webster, Cossins, Kennett, Hilton-Jones, and Vincent. Analysis and interpretation of data: Jacob, Viegas, Leite, Webster, Kennett, Morgan, and Vincent. Drafting of the manuscript: Jacob and Vincent. Critical revision of the manuscript for important intellectual content: Jacob, Viegas, Leite, Webster, Cossins, Kennett, Hilton-Jones, Morgan, and Vincent. Statistical analysis: Jacob and Webster. Obtained funding: Jacob and Vincent. Administrative, technical, and material support: Jacob, Viegas, Leite, Cossins, and Morgan. Study supervision: Leite, Webster, Kennett, Hilton-Jones, Morgan, and Vincent.
Financial Disclosure: Dr Vincent and the University of Oxford hold patents and receive royalties and payments for antibody tests.
Funding/Support: This study was funded partly by a Myasthenia Gravis Association/Muscular Dystrophy Campaign neuromuscular research fellowship and partly by the Oxford National Institute of Health Research Biomedical Research Centre.
Additional Contributions: David Beeson, PhD, provided the DNA for mouse AChR subunits and rapsyn for cell transfection experiments.