Accepted for Publication: February 21, 2012.
Published Online: May 21, 2012. doi:10.1001/archneurol.2012.377
Authors Contributions:Study concept and design: Daoud, Dion, and Rouleau. Acquisition of data: Daoud, Suhail, Sabbagh, Belzil, Szuto, Dionne-Laporte, Khoris, Camu, Salachas, Meininger, Mathieu, and Strong. Analysis and interpretation of data: Daoud and Salachas. Drafting of the manuscript: Daoud, Sabbagh, Belzil, and Salachas. Critical revision of the manuscript for important intellectual content: Suhail, Szuto, Dionne-Laporte, Khoris, Camu, Meininger, Mathieu, Strong, Dion, and Rouleau. Statistical analysis: Salachas. Obtained funding: Dion and Rouleau. Administrative, technical, and material support: Suhail, Szuto, Dionne-Laporte, Khoris, Camu, Salachas, Meininger, Mathieu, and Rouleau. Study supervision: Rouleau.
Financial Disclosure: None reported.
Funding/Support: This work was financially supported by the ALS Division of the Muscular Dystrophy Association, the Frick Foundation for ALS Research, and the Canadian Institutes of Health Research. Dr Daoud is supported by a postdoctoral fellowship from the ALS Society of Canada and the Canadian Institutes of Health Research. Dr Daoud was also supported by a postdoctoral fellowship from the ALS Association and the Fonds de Recherche en Santé du Québec. Dr Rouleau holds a Canada Research Chair in Genetics of the Nervous System and the Jeanne et J-Louis-Lévesque in Genetics of Brain Diseases.
Additional Contributions: We thank the subjects and their parents for their participating in this study. Annie Levert, DEC, provided technical assistance.