Accepted for Publication: November 1, 2011.
Author Contributions:Study concept and design: Whitwell, Weigand, and Jack. Acquisition of data: Roberts and Jack. Analysis and interpretation of data: Whitwell, Wiste, Weigand, Rocca, Knopman, Boeve, Petersen, and Jack. Drafting of the manuscript: Whitwell and Jack. Critical revision of the manuscript for important intellectual content: Wiste, Weigand, Rocca, Knopman, Roberts, Boeve, Petersen, and Jack. Statistical analysis: Wiste, Weigand, Rocca, and Jack. Obtained funding: Roberts and Jack. Administrative, technical, and material support: Roberts, Boeve, and Jack. Study supervision: Jack.
Financial Disclosure: None reported.
Funding/Support: This study was supported by grants U01-AG024904-01, R01-AG11378, P50-AG16574, U01-AG06786, R21-AG38736, R01-DC010367, R01-AG037491, K01-AG028573, U24-AG026395, R01-AG15866, R01-AG034676, R01-AG023195, and R01-HL70825 from the National Institutes of Health (NIH); grant 90BC0009 from the Department of Health and Human Services/Office of the Secretary; the Dana Foundation; the Alexander Family Alzheimer's Disease Research Professorship of the Mayo Foundation; and the Robert H. and Clarice Smith and Abigail Van Buren Alzheimer's Disease Research Program of the Mayo Foundation. Data collection and sharing for this project was funded by grant U01-AG024904 from the NIH (ADNI). The ADNI is funded by the National Institute on Aging; the National Institute of Biomedical Imaging and Bioengineering; and through generous contributions from Abbott, AstraZeneca AB, Bayer Schering Pharma AG, Bristol-Myers Squibb, Eisai Global Clinical Development, Elan Corporation, Genentech, GE Healthcare, GlaxoSmithKline, Innogenetics, Johnson and Johnson, Eli Lilly and Co, Medpace, Inc, Merck and Co, Inc, Novartis AG, Pfizer Inc, F. Hoffman-La Roche, Schering-Plough, Synarc, Inc, and nonprofit partners the Alzheimer's Association and Alzheimer's Drug Discovery Foundation, with participation from the US Food and Drug Administration. Private sector contributions to the ADNI are facilitated by the Foundation for the NIH (http:// www.fnih.org). The grantee organization is the Northern California Institute for Research and Education, and the study is coordinated by the Alzheimer's Disease Cooperative Study at the University of California, San Diego. The ADNI data are disseminated by the Laboratory for Neuroimaging at the University of California, Los Angeles.
Additional Contributions: Data used in preparation of this article were obtained from the ADNI database (http://adni.loni.ucla.edu). As such, the investigators within the ADNI contributed to the design and implementation of the ADNI and/or provided data but did not participate in data analysis or in the writing of this report.