Accepted for Publication: October 4, 2011.
Author Contributions: Study concept and design: DiMauro. Acquisition of data: Gutiérrez Ríos, Kalra, Wilson, Tanji, Akman, and DiMauro. Analysis and interpretation of data: Gutiérrez Ríos, Kalra, Wilson, Akman, Area Gómez, and Schon. Drafting of the manuscript: Gutiérrez Ríos, Wilson, Area Gómez, and DiMauro. Critical revision of the manuscript for important intellectual content: Kalra, Tanji, Akman, and Schon. Obtained funding: DiMauro. Administrative, technical, and material support: Gutiérrez Ríos and Wilson. Study supervision: Tanji, Area Gómez, Schon, and DiMauro.
Financial Disclosure: None reported.
Funding/Support: This work has been supported by National Institutes of Health grant HD32062 and the Marriott Mitochondrial Disorders Clinical Research Fund. Dr Area Gómez is supported by the Ellison Foundation, and Dr Gutiérrez Ríos, by a postdoctoral fellowship from Ministerio de Educacion y Ciencia, Madrid, Spain.