Accepted for Publication: March 18, 2011.
Author Contributions:Study concept and design: Gardener, Scarmeas, Sacco, and Wright. Acquisition of data: Sacco and Wright. Analysis and interpretation of data: Gardener, Scarmeas, Gu, Boden-Albala, Elkind, Sacco, DeCarli, and Wright. Drafting of the manuscript: Gardener. Critical revision of the manuscript for important intellectual content: Gardener, Scarmeas, Gu, Boden-Albala, Elkind, Sacco, DeCarli, and Wright. Statistical analysis: Gardener, Scarmeas, and Gu. Obtained funding: Elkind, Sacco, and Wright. Administrative, technical, and material support: Gardener and Gu. Study supervision: Scarmeas, Boden-Albala, Elkind, Sacco, and Wright.
Financial Disclosure: None reported.
Funding/Support: This work is supported by grants R37 NS 29993 and K02 NS 059729 from the National Institute of Neurological Disorders and Stroke, grant 0735387N from the American Heart Association, and the McKnight Brain Research Institute.
Role of the Sponsor: The funding sources were not involved in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, and approval of the manuscript.
Additional Contributions: Robert Delapaz, MD, provided clinical readings of the brain MRI scans. We are also very grateful to the staff of the NOMAS and in particular the project manager, Janet DeRosa, MPH.