Accepted for Publication: June 14, 2011.
Published Online: August 8, 2011. doi:10.1001/archneurol.2011.185
Author Contributions:Study concept and design: Marder, Gupta, Greenberg, Frohman, Awad, Bagert, and Stüve. Acquisition of data: Marder, Gupta, and Stüve. Analysis and interpretation of data: Marder, Frohman, Bagert, and Stüve. Drafting of the manuscript: Marder, Frohman, Bagert, and Stüve. Critical revision of the manuscript for important intellectual content: Marder, Gupta, Greenberg, Frohman, Awad, Bagert, and Stüve. Statistical analysis: Bagert and Stüve. Administrative, technical, and material support: Marder, Gupta, Frohman, Bagert, and Stüve. Study supervision: Gupta, Frohman, and Stüve.
Financial Disclosure: Dr Greenberg has received honoraria from the Multiple Sclerosis Association of America, American Academy of Neurology, and EMD Serono. He has received consulting fees from sanofi-aventis, the Greater Good Foundation, and DioGenix. He holds equity in DioGenix. He receives grant support from the Guthy-Jackson Charitable Foundation and Accelerated Cure Project.
Additional Contributions: We thank all patients and volunteers who participated in this study. MaryAnn Vignaux assisted in contacting and scheduling patients for ultrasonography assessments.