Accepted for Publication: June 10, 2011.
Published Online: August 8, 2011. doi:10.1001/archneurol.2011.182
Author Contributions: Dr Moro had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Lozano, Lang, and Moro. Acquisition of data: Castrioto, Poon, Fallis, and Moro. Analysis and interpretation of data: Castrioto, Lang, and Moro. Drafting of the manuscript: Castrioto and Moro. Critical revision of the manuscript for important intellectual content: Castrioto, Lozano, Poon, Lang, Fallis, and Moro. Statistical analysis: Castrioto. Obtained funding: Lozano. Administrative, technical, and material support: Lozano, Poon, Lang, Fallis, and Moro. Study supervision: Lozano and Moro.
Financial Disclosure: Dr Lozano is a consultant for Medtronic, St. Jude, and Boston Scientific. Dr Lang has served as an advisor for Abbott, Allon Therapeutics, AstraZeneca, Biovail, Boerhinger Ingelheim, Cephalon, Ceregene, Eisai, Medtronic, Lundbeck A/S, Novartis, Merck Serono, Solvay, and Teva; received grants from the Canadian Institutes of Health Research, Dystonia Medical Research Foundation, Michael J. Fox Foundation, National Parkinson Foundation, and Ontario Problem Gambling Research Centre; and served as an expert witness in cases related to the welding industry. Dr Moro has occasionally received honoraria from Medtronic for lecturing and consultant service. She has received research grant support from the Canadian Institutes of Health Research, CurePSP, and St. Jude Medical.
Additional Contributions: We thank Rajeev Kumar, MD, Janis Miyasaki, MD, and Jean Saint-Cyr, PhD, for the initial care of the patients. Christopher Meaney, BHS, helped with statistical analysis.