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Correspondence |

Microbleeds and Lacunar Infarcts in the Rotterdam Scan Study

Jiang Wu, MD, PhD; Hongliang Zhang, MD
Arch Neurol. 2011;68(10):1344-1345. doi:10.1001/archneurol.2011.230.
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Mesker and colleagues1 reported a predilection of cerebral microbleeds (CMBs) in the posterior brain regions, particularly the temporal lobes, in the general population. This study, along with several previous ones, draws increasing attention to cerebral microbleeds as measured by T2*-weighted magnetic resonance imaging (MRI) in both cerebral amyloid angiopathy and hypertensive vasculopathy.2 The authors concluded that the predilection of CMBs in the temporal lobes corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy in the general population. Before this assumption is confirmed by pathological examination, other factors such as hypertensive lacunar infarcts should also be taken into account in the interpretation of their results.

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October 1, 2011
Mariëlle M. F. Poels, MD; Dymph J. Mesker, MD; M. Arfan Ikram, MD, PhD; Monique M. B. Breteler, MD, PhD; Meike W. Vernooij, MD, PhD
Arch Neurol. 2011;68(10):1344-1345. doi:10.1001/archneurol.2011.231.
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