Accepted for Publication: February 11, 2011.
Author Contributions: Drs Deng and Siddique had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Deng, Bigio, and T. Siddique. Acquisition of data: Deng, Bigio, Zhai, Fecto, Ajroud, Shi, Yan, Mishra, Ajroud-Driss, Heller, Sufit, N. Siddique, Mugnaini, and T. Siddique. Analysis and interpretation of data: Deng, Bigio, Fecto, Mugnaini, and T. Siddique. Drafting of the manuscript: Deng, Bigio, Fecto, and T. Siddique. Critical revision of the manuscript for important intellectual content: Zhai, Ajroud, Shi, Yan, Mishra, Ajroud-Driss, Heller, Sufit, N. Siddique, and Mugnaini. Obtained funding: T. Siddique. Study supervision: Deng, Bigio, and T. Siddique.
Financial Disclosure: None reported.
Funding/Support: Support for this study was provided by grants NS050641, AG13854, and T32 AG20506 from the National Institutes of Health; the Les Turner ALS Foundation; the ALS Association; the Vena E. Schaff ALS Research Fund; the Harold Post Research Professorship; the Herbert and Florence C. Wenske Foundation; the David C. Asselin MD Memorial Fund; and the Les Turner ALS Foundation/Herbert and Florence C. Wenske Professorship. Dr Ajroud is a postdoctoral fellow of the Blazeman Foundation of ALS.