We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Editorials |

Reversible Cerebral Vasoconstriction Syndrome A Rose by Any Other Name?

Brian J. Anziska, MD; Christopher Dardis, MD; Steven R. Levine, MD
Arch Neurol. 2011;68(8):976-977. doi:10.1001/archneurol.2011.174.
Text Size: A A A
Published online


New neurological entities, either syndromes or diseases, continue to be described and defined in the 21st century. Neuromyelitis optica, postulated by some to be a variant of multiple sclerosis even in the late 20th century, has more recently been defined as a separate disease with its own pathogenesis, clinical description, diagnostic testing, and treatment.1

Reversible cerebral vasoconstriction syndrome (RCVS) has now been defined as a syndrome, but not a clear-cut disease entity.2 The syndrome typically presents with repeated thunderclap headaches over days to weeks. Cerebrovascular imaging reveals diffuse segmental constriction and dilatation of large and medium-sized intradural arteries. These abnormalities are transient and resolve within 3 months of clinical presentation. Convexity subarachnoid hemorrhage, intracerebral hemorrhage, seizures, and posterior reversible encephalopathy syndrome (PRES) occur in a minority of patients early, usually in the first week. Transient ischemic attacks and cerebral infarcts occur later.3 However, these complications are usually transient and resolve.2 Few patients are left with permanent sequelae. Results of cerebrospinal fluid testing are normal or show only a slight pleocytosis and elevated protein levels.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

2 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Collections
PubMed Articles
Clubbing with ecstasy. Temperature (Austin) ;1(3):160-1.