Accepted for Publication: January 4, 2011.
Published Online: March 14, 2011. doi:10.1001/archneurol.2011.32
Author Contributions:Study concept and design: Gilli and Bertolotto. Acquisition of data: Gilli, Perga, Caldano, Capobianco, and Malucchi. Analysis and interpretation of data: Gilli, Navone, Perga, Marnetto, Caldano, Pulizzi, Malucchi, and Bertolotto. Drafting of the manuscript: Gilli and Bertolotto. Critical revision of the manuscript for important intellectual content: Gilli, Navone, Perga, Marnetto, Caldano, Capobianco, Pulizzi, Malucchi, and Bertolotto. Statistical analysis: Gilli and Malucchi. Obtained funding: Gilli and Bertolotto. Administrative, technical, and material support: Gilli, Navone, Perga, Marnetto, Caldano, Capobianco, and Pulizzi. Study supervision: Gilli and Bertolotto.
Financial Disclosure: Drs Gilli, Caldano, Capobianco, Pulizzi, Malucchi, and Bertolotto report that they have been reimbursed by Merck-Serono, sanofi-aventis, Biogen Dompè, Novartis, and Bayer Schering for attending several conferences. Drs Gilli, Marnetto, Caldano, Capobianco, Pulizzi, Malucchi, and Bertolotto report that they have received fees for lectures by Merck-Serono, Biogen Dompè, Biogen Idec, Teva, and sanofi-aventis. Dr Bertolotto reports that he has received funds for research and for staff members from Merck-Serono, Biogen Dompè, Biogen Idec, Bayer Schering, Novartis, and sanofi-aventis.
Funding/Support: This study was supported by a grant from the Fondazione Italiana Sclerosi Multipla (FISM contract 2009/R/14). Financial support was also obtained from the Fondazione per la Ricerca Biomedica and from the San Luigi Gonzaga ONLUS (Organizzazione Non Lucrativa di Utilità Sociale).
Role of the Sponsor: Both the sponsors and the pharmaceutical companies had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Additional Contributions: We thank Rita Guerrieri, RNC, Marina Panealbo, RNC, Giuliana Savoldi, RNC, and Angela Zaccaria, RNC, for their nursing assistance during our study. We also thank Anna Messina, MSEd, and Daniele Dell’Anna for their excellent administrative support.